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王立峰 教授

发布时间 :2012-10-10文字 :王立峰浏览量 :

 

王立峰,教授,博导,国家“万人计划”科技领军人才

联系电话:025-86718658

邮箱(E-mail):wanglifeng_8@nufe.edu.cn.

王立峰教授致力于粮油食品资源高值化利用技术研究,着重于小麦及全谷物食品加工特性、营养评价研究,探索杂粮中酚类化合物功能作用的评估及机理,利用食品组分中蛋白(肽)预防糖尿病、肥胖等代谢综合征。第一或通讯作者身份在Ultrasonics SonochemistryJournal of Agricultural and Food ChemistryFood HydrocolloidsFood & FunctionJournal of Functional Foods等杂志发表SCI/EI论文50余篇,在《中国农业科学》、《中国食品学报》等CSCD核心期刊发表论文30余篇。授权国家发明专利20余件,公开国家发明专利40余件。参与起草国家粮油行业标准2项。

主要社会兼职为国家原粮及制品标准委员会委员,中国食品科学技术学会青年委员会副秘书长,中国粮油学会食品分会副会长,江苏省食品学会监事。同时担任科技部、教育部、农业部,国家自然科学基金等项目评审专家,《食品工业与科技》、《食品研究与开发》杂志编委,以及Journal of Agricultural and Food ChemistryFood HydrocolloidsFood ChemistryJournal of Functional FoodFood & Function等杂志审稿专家。

王立峰教授系国家高层次人才特殊支持计划科技领军人才,科技部创新人才推进计划人选,入选江苏省现代农业(小麦)产业技术体系岗位科学家,先后荣获上海市技术发明一等奖,江苏省科技进步二等奖,中国产学研合作创新奖(个人),中国食品科学技术学会杰出青年奖,全国优秀粮油科技工作者以及中国粮油学会科学技术奖一等奖,江苏省高校技术发明二等奖,南京市自然科学优秀论文二等奖。先后入选首批“全国粮食行业青年拔尖人才”(国家粮食和物资储备局),江苏省“333”工程中青年科学技术带头人(江苏省委组织部),江苏省“六大人才高峰计划”B 层次培养对象(江苏省人社厅),江苏省“双创博士”计划人选(江苏省科技厅),江苏省“青蓝工程”优秀青年骨干教师(江苏省教育厅),江苏省优秀硕士论文指导教师(江苏省教育厅)。

主要科研项目(主持):

国家自然科学基金面上项目:

基于Nrf2/ARE信号通路的薏米香豆酸糖苷抗氧化分子机制及构效关系研究,31571766,2016.01-2019.12;

二硫键分子构象对菜籽Napin蛋白消化性能影响及其消化产物吸收机制研究,31871729,2019.01-2022.12.

菜籽蛋白高气液界面活性与其分子结构的关联机制研究,32172147,2022.01-2025.12

国家重点研发计划子课题:

酶法制备食用菜籽蛋白(肽)技术研究,2016YFD0401401,2017.01-2020.12;

稻米、小麦、菜籽加工原料物质基础研究,2016YFD0400201,2017.01-2020.12.

米糠、麸皮梯次化利用关键技术研究及高值化产品开发与示范,2021YFD2100182,2022.01-2025.12

“863”计划:

活性肽功能因子代谢机制及其稳定性研究,2013AA102207-2,2013.01-2017.12.

国家农业成果转化项目:

固态发酵制备高效、安全菜籽蛋白肽生产技术中试,2012GB24490611,2012.04-2013.04;

基于生物发酵法制备菜籽功能性短肽技术中试及产业化生产,2014GB2C100318,2014.09-2016.09.

江苏省自然科学基金面上项目:

肽基菜籽蛋白水解物对小肠细胞摄入葡萄糖调控作用机制研究,BK20191408,2019.07-2021.06;

菜籽蛋白肽抗肿瘤作用机理及其稳定性研究,BK2010573,2010.07-2012.07;

薏米香豆酸糖苷抗增殖活性分子机制及构效关系研究,BK20141485,2014.07-2017.06.

江苏省科技支撑计划项目:

成品粮储存加工过程中危害因子分析、控制关键技术研究,BE2012764,2012.09-2015.09.

江苏省农业科技自主创新资金项目:

基于超微粉碎加工方式的功能性复配杂粮代餐食品生产关键技术研究与开发,CX(18)3040,2018.07-2021.06.

修饰菜籽肽结构鉴定、活性评价技术研究,CX(10)444,2010.06-2012.06.

近年来代表性论文(第一作者或通讯作者):

(1) Application of Ultrasound-Assisted Physical Mixing Treatment Improves In Vitro Protein Digestibility of Rapeseed Napin. Ultrasonics Sonochemistry, 2020, 105136. (IF: 7.279)

(2) Insoluble-bound polyphenols of adlay seed ameliorate H2O2-induced oxidative stress in HepG2 cells via Nrf2 signalling. Food Chemistry, 2020, 126865. (IF: 5.399)

(3) Enhancing the solubility and foam ability of rice glutelin by heat treatment at pH12: Insight into protein structure. Food Hydrocolloids, 2020, 103, 105626. (IF: 5.839)

(4) Insight into protein-starch ratio on the gelatinization and retrogradation characteristics of reconstituted rice flour. International Journal of Biological Macromolecules, 2020, 146, 524-529. (IF: 4.784)

(5) Insight into the effect of gluten-starch ratio on the properties of Chinese steamed bread (Mantou). International Journal of Biological Macromolecules, 2020,163, 1821-1827. (IF: 4.784)

(6) Synthesis, Purification, and Characterization of a Structured Lipid Based on Soybean Oil and Coconut Oil and Its Applications in Curcumin‐Loaded Nanoemulsions. European Journal of Lipid Science and Technology, 2020, 122. 2000086. (IF: 2.056)

(7) Assessment of the DPP-IV inhibitory activity of a novel octapeptide derived from rapeseed using Caco-2 cell monolayers and molecular docking analysis. Journal of Food Biochemistry, 2020, 44(10). (IF:1.662)

(8) Identification and Quantification of DPP-IV-Inhibitory Peptides from Hydrolyzed-Rapeseed-Protein-Derived Napin with Analysis of the Interactions between Key Residues and Protein Domains. Journal of Agricultural and Food Chemistry, 2019, 67(13), 3679-3690. (IF: 3.571)

(9) Influence of photooxidation on the lipid profile of rapeseed oil using UHPLC-QTOF-MS and multivariate data analysis. Analytical Methods, 2019, 11(22), 2903-2917. (IF:2.378)

(10) Physicochemical properties and interfacial dilatational rheological behavior at air-water interface of high intensity ultrasound modified ovalbumin: Effect of ionic strength. Food Hydrocolloids, 2019, 97, 105210. (IF: 5.839)

(11) Absorption and metabolism of peptide WDHHAPQLR derived from rapeseed protein and inhibition of HUVEC apoptosis under oxidative stress. Journal of Agricultural and Food Chemistry, 2018, 66(20), 5178-5189. (IF: 3.571)

(12) Transepithelial transport of YWDHNNPQIR and its metabolic fate with cytoprotection against oxidative stress in human intestinal Caco-2 cells. Journal of Agricultural and Food Chemistry, 2017, 65(10), 2056-2065. (IF: 3.571)

(13) Identification and anti-tumour activities of phenolic compounds isolated from defatted adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) seed meal. Journal of Functional Foods, 2016, 26, 394-405. (IF: 3.197)

(14) Separation and purification of an anti-tumor peptide from rapeseed (Brassica campestris L.) and the effect on cell apoptosis. Food & Function, 2016, 7(5), 2239-2248. (IF: 3.241)

(15) Structural characterization of phenolic compounds and antioxidant activity of the phenolic-rich fraction from defatted adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) seed meal. Food Chemistry, 2016, 196, 509-517. (IF: 5.399)

(16) Study on antioxidant activity and amino acid analysis of rapeseed protein hydrolysates. International Journal of Food Properties, 2016, 19(9), 1899-1911. (IF: 1.398)

(17) Study of the fermentation conditions and the antiproliferative activity of rapeseed peptides by bacterial and enzymatic cooperation. International Journal of Food Science & Technology, 2015, 50(3), 619-625. (IF: 2.281)

(18) Phytochemical profiles and antioxidant activity of adlay varieties. Journal of Agricultural and Food chemistry, 2013, 61(21), 5103-5113. (IF: 3.571)

(19) Protective effect of polyphenols extract of adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) on hypercholesterolemia-induced oxidative stress in rats. Molecules, 2012, 17(8), 8886-8897. (IF: 3.060)

(20) Dietary a novel structured lipid synthesized by soybean oil and coconut oil alter fatty acid metabolism in C57BL/6J mice[J]. Food Bioscience, 2021, 44: 101396. (IF:3.2)

(21) A novel smartphone-based electrochemical cell sensor for evaluating the toxicity of heavy metal ions Cd2+, Hg2+, and Pb2+ in rice[J]. Analytical and Bioanalytical Chemistry, 2021(16). (IF:3.6)

(22) A biomimetic "intestinal microvillus" cell sensor based on 3D bioprinting for the detection of wheat allergen gliadin. Bioelectrochemistry, 2021 ,142:107919. (IF:4.7)

(23) Preparation and characteristics of high internal phase emulsions stabilized by rapeseed protein isolate[J]. LWT- Food Science and Technology, 2021(1):111753. (IF:4)

(24) Yao Y, Xiong W, Chen L, et al. Synergistic growth-inhibition effect of Quercetin and N-Acetyl-L-cysteine against HepG2 cells relying on the improvement of Quercetin stability[J]. Food Chemistry, 2022,131729. (IF:6.3)

(25) Hu X, Xu F, Li J, et al. Ultrasonic-assisted extraction of polysaccharides from coix seeds: Optimization, purification, and in vitro digestibility[J]. Food Chemistry, 2022, 374: 131636. (IF:6.3)